The Effect of Structural Microheterogeneity on the Initiation and Propagation of Ectopic Activity in Cardiac Tissue by
نویسندگان
چکیده
THE EFFECT OF STRUCTURAL MICROHETEROGENEITY ON THE INITIATION AND PROPAGATION OF ECTOPIC ACTIVITY IN CARDIAC TISSUE by Marjorie Letitia Hubbard Department of Biomedical Engineering Duke University Date:_______________________ Approved: ___________________________ Craig Henriquez, Supervisor ___________________________ Roger C. Barr ___________________________ Nenad Bursac ___________________________ Donald Rose ___________________________ Madison Spach An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biomedical Engineering in the Graduate School of Duke University 2010 Copyright by Marjorie Letitia Holden Hubbard 2010
منابع مشابه
Effect of Transient Congenital Hypothyroidism on Oxidative Stress in Cardiac Tissue of Adult Male Rats
Introduction: Increased oxidative stress is involved in the pathology of cardiovascular disease. Transient congenital hypothyroidism (TCH) leads to a variety of heart disorders during adulthood. In this study, the effect of TCH on antioxidant and oxidant systems in the serum and left cardiac ventricle of adult male rats was investigated. Materials and Methods: TCH was induced by administrating ...
متن کاملEFFECT OF 8 WEEKS OF INCREMENTAL ENDURANCE TRAINING ON THE ACTIVITY OF SUPEROXIDE DISMUTASE ENZYME AND MALONDIALDEHYDE LEVELS OF CARDIAC TISSUE OF RATS WITH TYPE 2 DIABETES
Background: Diabetes and its oxidative stress increase the effects of this disease on heart tissue. On the other hand, exercise improves the antioxidant status of heart tissue. The aim of this study was to investigate the effect of 8 weeks of increased endurance training on superoxide dismutase activity and malondialdehyde levels in the heart tissue of mice with type 2 diabetes. Methods: In th...
متن کاملTHE EFFECT OF AEROBIC TRAINING ON MUSCLE ANGIOGENESIS AND DOWNSTREAM FACTORS OF PI3KR2 PATHWAY IN CARDIAC TISSUE OF DIABETIC RATS
Background & Aims: Regarding the effect of diabetes on vascularization processes and since the beneficial effects of aerobic exercise on the cardiovascular system have been proven, therefore, the aim of this study was to determine the effect of aerobic exercise on muscle angiogenesis and downstream factors of the PI3KR2 pathway in cardiac tissue of diabetic rats. Materials & Methods: Twenty di...
متن کاملStructural changes of cardiac tissue in response to L-carnitine supplementation during endurance training in Wistar male rats toxicated by steroid anabolic hormone
Introduction: The aim of this study was to investigate the structural changes of cardiac tissue in response to L-carnitine supplementation and endurance training in Wistar male rats toxicated by steroid anabolic hormone. Methods: 36 male Wistar rats aged 8-12 weeks (weight 195±7.94g) were randomly divided into six groups: Control, Non-treated, Boldenone (5 mg/kg), L-carnitine (100 mg pe...
متن کاملKinetic Investigation of Myeloperoxidase upon Interaction with Copper, Cadmium, and Lead Ions
Background: Myeloperoxidase (MPO), which is abundantly expressed in neutrophils, catalyzes the formation of a number of reactive oxidant species. However, evidence has emerged that MPO-derived oxidants contribute to tissue damage and initiation and propagation of inflammatory diseases, particularly, cardiovascular diseases. Therefore, studying the regulatory mechanisms of the enzyme activity is...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2010